Laboratory Medicine

Test catalogue

Sirolimus
Test Name Sirolimus (Rapamycin)
Specimen Type / Requirements Container Type = Lavender Minimum Venous Volume = 1 mL whole blood
Specimen Handling Collection Instructions: Collect sample in a lavender top and send to core lab. Sample should be well mixed at time of collection to prevent platelet clumping. Write your initials, date and time of collection on the collection label. Stability: Stable for up to 28 days at 15-25◦C and 2-8◦C or 6 months at -20◦C. Freeze only once Transportation: Transport at room temperature within 1 hour of collection. Sample Rejection Criteria: Plasma, clotted sample, Grossly hemolyzed samples, Unlabeled or Not Sufficient Quantity Samples will be rejected.
Required Documentation
Turnaround Time (TAT) 1 day	Test Utilization
Reference Value 2 mg/d dose: 4.5-14.0 ug/L 5 mg/d dose:10-28 ug/L Toxic: >30 ug/L Target therapeutic range may vary depending on type of transplant, treatment protocols, and time post-transplant. Interpret results using this information and any clinical signs and symptoms of rejection or toxicity.
Test Code SIRO	Methodology Competitive Binding Immunoassay
Testing Location SMH-Biochemistry	Other Information Last Updated: July 14, 2026

Sirolimus

Test Name

Sirolimus (Rapamycin)

Specimen Type / Requirements

Container Type = Lavender

Minimum Venous Volume = 1 mL whole blood

Specimen Handling

Collection Instructions: Collect sample in a lavender top and send to core lab. Sample should be well mixed at time of collection to prevent platelet clumping. Write your initials, date and time of collection on the collection label.

Stability: Stable for up to 28 days at 15-25◦C and 2-8◦C or 6 months at -20◦C. Freeze only once

Transportation: Transport at room temperature within 1 hour of collection.

Sample Rejection Criteria: Plasma, clotted sample, Grossly hemolyzed samples, Unlabeled or Not Sufficient Quantity Samples will be rejected.

Required Documentation

Turnaround Time (TAT)

1 day

Test Utilization

Reference Value

2 mg/d dose: 4.5-14.0 ug/L

5 mg/d dose:10-28 ug/L

Toxic: >30 ug/L

Target therapeutic range may vary depending on type of transplant, treatment protocols, and time post-transplant. Interpret results using this information and any clinical signs and symptoms of rejection or toxicity.

Test Code

SIRO

Methodology

Competitive Binding Immunoassay

Testing Location

SMH-Biochemistry

Other Information

Last Updated: July 14, 2026