Test performed at:

Acetaminophen: (Tylenol, Datril, Phenacetin, Paracetamol)
Test Name Acetaminophen: (Tylenol, Datril, Phenacetin, Paracetamol)
Specimen Type / Requirements Container Type = 1 Red Top Minimum Testing Volume = 3 mL Serum Tube must fill to at least ½ or greater of its vacuum capacity
Specimen Handling Collection Instructions: Collect sample in red top tube. Avoid gold top (SST). When evaluating for possible toxicity, sample should be drawn 4-6 hour post-ingestion. Collect a second sample three to four hours later. Write your initials, date and time of collection on the collection label or requisition. Laboratory Staff Instructions: Separate samples from cells as soon as possible. Repeated freezing and thawing of samples should be avoided. Rejection Criteria: Gel separator, unlabeled or not sufficient quantity samples will be rejected. Stability: Stable At room temperature: up to 24 hours. Refrigerated at 2-8°C: up to 7 days. Frozen at -20°C: up to 180 days Transportation: Send sample to core lab as soon as possible.
Required Documentation
Turnaround Time (TAT) 1 hour for Trauma / Stat 2 hours for routine
Reference Value Abnormal: > 66 µmol/L Interpretation: Potentially toxic acetaminophen level depending on clinical context and time since last ingestion. Please refer to Rumack-Matthew nomogram if applicable (i.e., in suspected single acute ingestion). Critical: > 660 µmol/L Interpretation: Suggests toxicity in patients presenting ≥6 hours following single acute acetaminophen ingestion. Please refer to Rumack-Matthew nomogram.
Test Code ACET	Methodology Enzymatic / Colorimetric
Testing Location SMH-Biochemistry	Other Information Last Updated: November 20, 2023

Acetaminophen: (Tylenol, Datril, Phenacetin, Paracetamol)

Test Name

Acetaminophen: (Tylenol, Datril, Phenacetin, Paracetamol)

Specimen Type / Requirements

Container Type = 1 Red Top

Minimum Testing Volume = 3 mL Serum

Tube must fill to at least ½ or greater of its vacuum capacity

Specimen Handling

Collection Instructions: Collect sample in red top tube. Avoid gold top (SST). When evaluating for possible toxicity, sample should be drawn 4-6 hour post-ingestion. Collect a second sample three to four hours later. Write your initials, date and time of collection on the collection label or requisition.

Laboratory Staff Instructions: Separate samples from cells as soon as possible. Repeated freezing and thawing of samples should be avoided.

Rejection Criteria: Gel separator, unlabeled or not sufficient quantity samples will be rejected.

Stability: Stable At room temperature: up to 24 hours. Refrigerated at 2-8°C: up to 7 days. Frozen at -20°C: up to 180 days

Transportation: Send sample to core lab as soon as possible.

Required Documentation

Turnaround Time (TAT)

1 hour for Trauma / Stat
2 hours for routine

Reference Value

Abnormal: > 66 µmol/L

Interpretation: Potentially toxic acetaminophen level depending on clinical context and time since last ingestion.
Please refer to Rumack-Matthew nomogram if applicable (i.e., in suspected single acute ingestion).

Critical: > 660 µmol/L

Interpretation: Suggests toxicity in patients presenting ≥6 hours following single acute acetaminophen ingestion.
Please refer to Rumack-Matthew nomogram.

Test Code

ACET

Methodology

Enzymatic / Colorimetric

Testing Location

SMH-Biochemistry

Other Information

Last Updated: November 20, 2023